Top 8 Best Enzyme Cleaners for Dog Urine

The Best Enzyme Cleaners for Dog Urine

Potty problems present one of the greatest challenges to dog owners. Even with potty training, some dogs may pee indoors due to environmental or health conditions. To avoid staining to your surfaces and a buildup of odors in your home, you should invest in a natural, enzymatic cleaner. A good cleaner will help you avoid permanent damage to your surfaces while also keeping your dog healthy. Enzymatic cleaners use bacteria and enzymes to break down the compounds in your pet’s urine and eliminate stains and odors. We researched and came up with a list of the 8 best enzyme cleaners for dog urine, which should serve as a handy guide for any pet parent looking to eliminate urine stains and odors in their home.

The 8 Best Enzyme Cleaners for Dog Urine

Preview Name Ratings
Nature’s Miracle Urine Destroyer Stain and Residue Eliminator Buy On Amazon
Pet Stain and Odor Miracle Buy On Amazon
Rocco & Roxie Stain and Odor Eliminator Buy On Amazon
Simple Solution Extreme enzymatic cleaner for dog urine Buy On Amazon
OdoBan Odor Eliminator Buy On Amazon
Nilodor Urine Digester Buy On Amazon
NonScents Pet Odor & Stain Remover Spray Buy On Amazon
Bubba’s Super Strength Commercial Enzyme Cleaner Buy On Amazon

1. Nature’s Miracle Urine Destroyer Stain and Residue Eliminator

Features

  • Size: 32 Oz, 64 Oz, 128 Oz
  • Weights: 2.5 Pounds, 4.4 Pounds, 8 Pounds
  • Best use: Suitable for all dog breeds

Key Features

  • Suitable for carpets, treated hardwood floors, tile, and linoleum
  • Tough on strong urine smell and sticky residue
  •  It is a bacteria-based formula for odor elimination
  • Targeted urine destroyer
  • Eliminates odors leaving a light, fresh scent

Nature’s miracle urine destroyer uses its natural formula to produce bacteria that attack dog pee. When you spray it on a urine spot, it clears the stains and residue that the urine leaves behind after drying. The advanced formula ensures that bacteria stay active until all the urine stains and odors are eliminated. This cleaner also has odor locking technology that traps and eliminates urine smell as soon as they come into contact. When sprayed on a pee trail, the bacteria will remove pheromones, hence breaking the re-soiling cycle. It is friendly on most fabrics, treated hardwood floors, tiles, and pet bedding.

Pros

  • Works on invisible stains
  • Can eliminate dried stains and old odors
  • Pet and child-friendly formula

Cons

  • The smell can overwhelm some individuals

Buy On Amazon 

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2. Pet Stain and Odor Miracle

Features

  • Size: 32 Oz (10.7 x 4.9 x 2.9 inches), 1 Gallon (11.8 x 6.1 x 5.8 inches)
  • Weight: 2.3 Pounds, 8.65 Pounds
  • Variants: Fall Spice Scent, Spring Mint Scent
  • Best use: Dog & Cat Urine, Feces, Drool, Vomit

Key Features

  • Multi-surface formula for use on most fabrics, hardwood, tiles, and upholstery
  • Completely eliminates pet stains and odors
  • Powerful natural enzyme formula that is safe for use with children and pets
  • 100% Cash-back guarantee in case you don’t like the cleaner

The Sunny and Honey Pet Stain and Odor miracle are one of our 8 best enzyme cleaners for dog urine because of its versatility. This product can be used on both dogs and cats to fight odors and stains from urine, feces, drool, and vomit. Its natural formula is friendly on all surfaces, and it has a pleasant smell to help fight odors. It uses enzymes that are released as soon as the formula comes in contact with dog urine to fight odors and stains. It works on both new and old stains.

Pros

  • Fights all organic pet stains
  • Does not leave a residue after cleaning
  • Instant stain removal
  • Pet and child-friendly product

Cons

  • Is ineffective on silk material
  • Peppermint scent can be upsetting to some individuals

Buy On Amazon 

Best Alternative Product on Chewy: Petzyme Pet Stain & Odor Remover

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3. Rocco & Roxie Stain and Odor Eliminator

Features

  • Size: 32 Oz (5 x 2 x 10 inches), 1 Gallon (6 x 6 x 12 inches)
  • Weight: 2 Pounds, 8 Pound
  • Best use: for all dog breeds

Key Features

  • Effectively eliminates odors, stains, and residue
  • Enzyme-activated bacterial action
  • Works on all surfaces
  • Cash back guarantee
  • Gentle and safe for all fabrics

The Rocco and Roxie stain remover is the top-rated enzyme cleaner for dog urine, stains, and odors. This product is versatile and can be used on cat stains, and to remove stubborn stains from everyday fabric. This effective formula will eliminate yellow stains from urine and feces within 24 hours of application. It is also effective in removing stains from spills, drool, and vomit. It uses enzymatic bacteria that feeds on ammonia crystals and organic matter in dog urine to leave your home looking and smelling fresh.

Pros

    • Free from dangerous propellants
  • Gentle on most fabrics (CRI certified)
  • Pet and child-friendly formulation
  • A multi-use product

Cons

  • May destroy light fabrics

Buy On Amazon 

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4. Simple Solution Extreme enzymatic cleaner for dog urine

Features

  • Size: 32 Oz (4.5 x 2.8 x 11.1 inches), 128 Oz (7.1 x 7.1 x 11.9 inches)
  • Weight: 2.3 Pounds, 8.79 Pounds
  • Variations: Original, Scented
  • Best Use: All dog breeds

Key Features

  • Has Powerful formula to eliminate the toughest stains and odors
  • Pro-bacteria formulation to decompose urine compounds
  • Works on most organic pet stains
  • Comes with a 3-in-1 nozzle sprayer
  • Enzymatic action discourages repeat marking
  • Safe for domestic use

This enzymatic cleaner for dog urine is up to 3X more powerful than most ordinary cleaners. It is designed to remove stubborn stains and eliminate odors through enzymatic action. This product is able to break down odors and clean stains. The enzymes also destroy pheromones in the dog’s urine, which discourages repeat marking. Despite its strength, this cleaner can be used on most water-safe surfaces, including light fabrics.

Pros

  • Pro-bacterial action promotes faster stain removal
  • Leaves no residue
  • Pet and child-friendly formula

Cons

  • May not be effective on wood surfaces if the wood absorbs dog urine

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5. OdoBan Odor Eliminator

Features

  • Size: 32 Oz, 1 Gallon
  • Weight: 12 pounds
  • Color: Clear
  • Best Use: All indoor pets

Key Features

  • Comes with a ready-to-use trigger bottle
  • Natural eucalyptus scent
  • Disinfects and kills 99.9% of germs
  • Versatile: Can be used to eliminate stains and odors from smoke, mildew, mold, water damage, and organic pet stains
  • Suitable for use on carpets, upholstery, tiles, ceramics, clothes and many other surfaces

As a pet owner, you can use OdoBan to clean, disinfect, and deodorize surfaces in your house. The OdoBan is effective at eliminating unpleasant smells from dog urine, feces, and vomit. This product can help neutralize all odors within your home. It is made of industrial-strength formula, so you can use this cleaner in both commercial and residential settings. OdoBan is fabric-friendly and can be used to remove dog urine stains from pet bedding, drapes, car upholstery, tiles, clothes, drywall, concrete, basins, tubs, and many more.

Pros

  • Residue-free action
  • Industrial strength formulation keeps your house free from smells
  • Eliminates Germs
  • Pleasant Eucalyptus scent leaves your house feeling fresh

Cons

  • The formulation is highly concentrated and requires diluting

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6. Nilodor Urine Digester

Features

  • Size: Quart, Gallon, 5 Gallon
  • Weight: 8.65 Pounds
  • Variations: Original, Red Clover Tea, Tango Mango, Spring Mint, Cucumber Melon
  • Best Use: All Dog Breeds

Key Features

  • Bio-enzymatic odor-neutralization action
  • Carpet and Rug Institute Approved for use on fabrics
  • Multiple fragrances to leave your home feeling fresh
  • Versatile: Can be used on all surfaces, for different types of odors
  • Digests and removes odors at the source

This product features a bio-enzymatic cleaner paired with fragrances that remove odors. Once applied, the bacteria work round the clock, seeking out the sources of odor, leaving a fresh fragrance after cleaning. The Nilodor Urine Digester is easy to use, as you can apply it by mopping or spraying around fabrics, carpeting, and hard surfaces. The Nilodor formula contains various enzymes, bacteria, and odor-fighting agents to give you a proper cleaning job. The powerful formula helps to clear stains within hours of application.

Pros

  • Effective on most surfaces
  • Will work on any amount of dog urine
  • Multi-use product

Cons

  • The industrial smell can be unpleasant to some

Buy On Amazon 

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7. NonScents Pet Odor & Stain Remover Spray

Features

  • Size: 1 Gallon
  • Weight: 4.4 Pounds
  • For use on All Dog and Cat Breeds

Key Features

  • Molecular stain and odor removal
  • Non-toxic and safe to use around the house
  • Effective on all surfaces
  • 100% Cash Back Guarantee

The NonScents pet odor remover makes our top 8 best enzyme cleaners for dog urine list because it is made of pet-friendly, non-toxic materials. The product is multi-purpose, and you can use it to eliminate organic stains from both cats and dogs. You can also use it to remove smells brought by stale food, fruits, and vegetables. It is safe to use on multiple surfaces, and since it contains no chemical additives, it can be used on the most sensitive pets.

Pros

  • Non-toxic and safe for indoor use
  • Fast-acting; odor elimination within an hour
  • Improves Indoor air quality

Cons

  • Can bleach fabric with running colors
  • Stains wood and painted surfaces

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8. Bubba’s Super Strength Commercial Enzyme Cleaner

Features

  • Size: 32 Oz (8.3 x 4.8 x 2.8 inches), 1 Gallon (6 x 6 x 12 inches)
  • Weight: 2.3 pounds, 8 Pounds
  • Suitable for all pets

Key Features

  • Professional grade cleaning solution for permanent odor and stain removal
  • Dormant bacteria formulation for lifetime effectiveness
  • Carpet and Rug Institute Certified- Fabric friendly solution
  • Cash Back Guarantee
  • Multiple uses

The Bubba Commercial Enzyme Cleaner is great for stubborn stains and odors. It can be paired with home carpet cleaners and steam-machines for a proper cleaning job. The formulation includes dormant bacteria, which become active once they hit the stain, making this cleaner a powerful solution against pet urine. It can also eliminate long-standing odors and dried-in stains. The product comes with a money-back guarantee in case it doesn’t effectively take care of your cleaning needs.

Pros

  • Versatile products; can be used in the kitchen, bathroom, hallways, and pet playpens.
  • Dormant bacteria formulation improves effectiveness when cleaning stains
  • Carpet and Rug Institute Certified

Cons

  •  Industrial smell can be upsetting to some people

Buy On Amazon 

Best Alternative Product on Chewy: Stuart Pet Supply Co. Professional Strength Pet Stain & Odor Eliminator

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Conclusion

While all enzymatic cleaners work the same way to break down stains in dog urine, not all cleaners are equal. Each product contains a different type of enzyme for different cleaning actions. As a dog owner, it is up to you to select a cleaner with the right combination of enzymes for your dog’s stain. The cleaners we have described in this article are effective, natural, and safe. You should, however, keep them out of reach for pets and children. We hope that this article guides you to identify the best cleaners for your home and pet needs. 

Also check out The 8 Best Pet Odor Eliminators